Comparative analysis of platelets adhesion to the surface of Ta-based ceramic coatings deposited by magnetron sputtering
Authors:
Open Access
- 1 April 2020
- conference paper
- Published by IOP Publishing in Journal of Physics: Conference Series
- Vol. 1492 (1)
Abstract
The adhesion of platelets to the surface of implants and stents depends on the material’s properties, such as surface roughness, topography and wettability. The present study analyzes the composition and surface properties of nanostructured Ta, Ta2O5 and TaON coatings and their correlation with the adhesion of platelets. The surface morphology and topography were observed by atomic force microscopy and electron scanning microscopy; while the elemental distribution and chemical composition were analyzed by energy dispersive X-ray spectroscopy. The coated surfaces’ advancing contact angles were evaluated by tensiometric measurements. The surface free energy (SFE) was calculated by the Owens, Wendt, Rabel and Kaeble method. The results of in vitro tests demonstrated that the deposition of Ta-based coatings leads to a decrease in the platelets adhesion and agglomeration ability.Keywords
This publication has 10 references indexed in Scilit:
- Coronary Stents: The Impact of Technological Advances on Clinical OutcomesAnnals of Biomedical Engineering, 2015
- Surface chemistry and cytotoxicity of reactively sputtered tantalum oxide films on NiTi platesThin Solid Films, 2015
- Peripheral Drug-Eluting TechnologyCardiology Clinics, 2015
- Growth and characteristics of tantalum oxide thin films deposited using thermionic vacuum arc technologyJournal of Applied Physics, 2010
- Platelet receptors and signaling in the dynamics of thrombus formationHaematologica, 2009
- Progressive stent technologies: new approaches for the treatment of cardiovascular diseasesExpert Opinion on Drug Delivery, 2006
- Blood Compatibility of Titanium Oxides with Various Crystal Structure and Element DopingJournal of Biomaterials Applications, 2003
- Evaluation of metal allergies in patients with coronary stentsContact Dermatitis, 2002
- Nickel and molybdenum contact allergies in patients with coronary in-stent restenosisThe Lancet, 2000
- Estimation of the surface free energy of polymersJournal of Applied Polymer Science, 1969