An overview of the prevalence of 25‐hydroxy-vitamin D inadequacy amongst elderly patients with or without fragility fracture in the United Kingdom
- 20 January 2006
- journal article
- review article
- Published by Taylor & Francis in Current Medical Research and Opinion
- Vol. 22 (2) , 405-415
Abstract
Background: Many studies have investigated the prevalence of 25-hydroxy-vitamin D inadequacy throughout the world and found a high prevalence of 25-hydroxy-vitamin D inadequacy in older patients, particularly those with fragility fracture.Scope: To review the findings from vitamin D audits from six units across the UK and compare with previously published data from around the world. Results from four units have been previously published (Belfast, Glasgow, London and Medway) and this paper presents new data from Southampton and Carshalton, and further sub-analysis of the data from Medway.Findings: Three audits of patients attending metabolic bone clinics (Carshalton, Medway and Southampton) identified 954 patients, of which overall 49% had a prior fragility fracture. Mean 25‐hydroxy-vitamin D levels ranged from 47.7 nmol/L to 62.4 nmol/L. Of these patients 72.9–88.9% had a 25‐hydroxy-vitamin D level < 80 nmol/L, 68.8–83.3% < 70 nmol/L and 37.5–59.1% < 50 nmol/L. The mean age of patients ranged from...Keywords
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