Durable epigenetic silencing with a TALE-based editor
- 8 October 2025
- journal article
- editorial
- Published by Springer Nature in Nature Biotechnology
- Vol. 44 (9) , 1-3
Abstract
No abstract availableKeywords
This publication has 10 references indexed in Scilit:
- Design of optimized epigenetic regulators for durable gene silencing with application to PCSK9 in nonhuman primatesNature Biotechnology, 2025
- Why do lipid nanoparticles target the liver? Understanding of biodistribution and liver-specific tropismMolecular Therapy - Methods & Clinical Development, 2025
- A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levelsNature Medicine, 2025
- Durable and efficient gene silencing in vivo by hit-and-run epigenome editingNature, 2024
- Targeting proprotein convertase subtilisin/kexin type 9 (PCSK9): from bench to bedsideSignal Transduction and Targeted Therapy, 2024
- Lipid nanoparticles for mRNA deliveryNature Reviews Materials, 2021
- Genome-wide programmable transcriptional memory by CRISPR-based epigenome editingCell, 2021
- Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL CholesterolNew England Journal of Medicine, 2020
- Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic EditingCell, 2016
- Breaking the Code of DNA Binding Specificity of TAL-Type III EffectorsScience, 2009