The action of substance P on mesencephalic reticular and substantia nigral neurones of the rat
Authors:
- 1 February 1976
- journal article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 32 (2) , 214-215
Abstract
Extracellular recordings were made from neurones in the mesencephalic reticular formation and substantia nigra of the rat which was anaesthetized with urethane 1.5–2 g/kg i.p. Out of 44 cells tested 42 were excited by Substance P applied iontophoretically and in some cases this excitation was rapid. Evidence is presented for Substance P as a putative excitatory transmitter onto reticular and nigral neurones possibly released from primary sensory afferents.Keywords
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