Accessory Genomes Drive Independent Spread of Carbapenem-Resistant Klebsiella pneumoniae Clonal Groups 258 and 307 in Houston, TX
Open Access
- 26 April 2022
- journal article
- research article
- Published by American Society for Microbiology in mBio
- Vol. 13 (2) , e0049722
Abstract
The prevalence of carbapenem-resistant Klebsiella pneumoniae (CR Kp ) infections in nosocomial settings remains a public health challenge. High-risk clones such as clonal group 258 (CG258) are particularly concerning due to their association with bla KPC carriage, which can severely complicate antimicrobial treatments.Keywords
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Funding Information
- University of Texas System (STARS Award)
- Texas Medical Center Health Policy Institute Funding Program
- US Veterans Affairs Merit Review Award (5I01 BX003741)
- University of Texas Health Science Center (Presidential Award)
- HHS | NIH | National Institute of Allergy and Infectious Diseases (K01AI148593-01)
- HHS | NIH | National Institute of Allergy and Infectious Diseases (R01AI143910)
- HHS | NIH | National Institute of Allergy and Infectious Diseases (UM1AI104681)
- HHS | NIH | National Institute of Allergy and Infectious Diseases (K24AI12196, R01AI134637, R01AI148342-01, R21AI143229, P01AI152999-01)
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