Copper-Catalyzed Alkylation of Benzoxazoles with Secondary Alkyl Halides
Authors:
- 9 March 2012
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 14 (7) , 1748-1751
Abstract
Copper-catalyzed direct alkylation of benzoxazoles using nonactivated secondary alkyl halides has been developed. The best catalyst is a new copper(I) complex (1), and the reactions are promoted by bis[2-(N,N-dimethylamino)ethyl] ether.Keywords
This publication has 53 references indexed in Scilit:
- Palladium-Catalyzed Alkylation of ortho-C(sp2)-H Bonds of Benzylamide Substrates with Alkyl HalidesOrganic Letters, 2011
- Direct Alkylation of Heteroaryls Using Potassium Alkyl- and AlkoxymethyltrifluoroboratesOrganic Letters, 2011
- The Catalytic Ability of Various Transition Metals in the Direct Functionalization of Aromatic C-H BondsChemistry – A European Journal, 2011
- Recent advances in the transition metal-catalyzed twofold oxidative C–H bond activation strategy for C–C and C–N bond formationChemical Society Reviews, 2011
- Nickel‐Catalyzed Direct C-H Arylation and Alkenylation of Heteroarenes with Organosilicon ReagentsAngewandte Chemie International Edition, 2010
- Auxiliary-Assisted Palladium-Catalyzed Arylation and Alkylation of sp2 and sp3 Carbon−Hydrogen BondsJournal of the American Chemical Society, 2010
- Palladium(II)‐Catalyzed ortho Alkylation of Benzoic Acids with Alkyl HalidesAngewandte Chemie International Edition, 2009
- Palladium- and Copper-Catalyzed Arylation of Carbon−Hydrogen BondsAccounts of Chemical Research, 2009
- Secondary Alkyl Halides in Transition‐Metal‐Catalyzed Cross‐Coupling ReactionsAngewandte Chemie International Edition, 2009
- Direct Functionalization of Nitrogen Heterocycles via Rh-Catalyzed C−H Bond ActivationAccounts of Chemical Research, 2008