Axially Coordinated Gold Nanoclusters Tailoring Fe–N–C Nanozymes for Enhanced Oxidase‐Like Specificity and Activity
Open Access
- 9 January 2024
- journal article
- research article
- Published by Wiley in Advanced Science
- Vol. 11 (11) , e2306911
Abstract
Metal–organic frameworks (MOF) derived nitrogen‐doped carbon‐supported monodisperse Fe (Fe–N–C) catalysts are intensively studied, but great challenges remain in understanding the relationship between the coordination structure and the performance of Fe–N–C nanozymes. Herein, a novel nanocluster ligand‐bridging strategy is proposed for constructing Fe‐S1N4 structures with axially coordinated S and Au nanoclusters on ZIF‐8 derived Fe–N–C (labeled Aux/Fe‐S1N4‐C). The axial Au nanoclusters facilitate electron transfer to Fe active sites, utilizing the bridging ligand S as a medium, thereby enhancing the oxygen adsorption capacity of composite nanozymes. Compared to Fe‐N‐C, Aux/Fe‐S1N4‐C exhibits high oxidase‐like specificity and activity, and holds great potential for detecting acetylcholinesterase activity with a detection limit of 5.1 µU mL−1, surpassing most reported nanozymes.Keywords
Funding Information
- National Natural Science Foundation of China (22301183, 22071202, 21931009, 21721001, 22022018)
This publication has 37 references indexed in Scilit:
- Adsorbed Intermediates in Oxygen Reduction on Platinum Nanoparticles Observed by In Situ IR SpectroscopyAngewandte Chemie International Edition, 2018
- In vivo guiding nitrogen-doped carbon nanozyme for tumor catalytic therapyNature Communications, 2018
- Tumor Catalytic–Photothermal Therapy with Yolk–Shell Gold@Carbon NanozymesACS Applied Materials & Interfaces, 2018
- ZnAl‐Hydrotalcite‐Supported Au25Nanoclusters as Precatalysts for Chemoselective Hydrogenation of 3‐NitrostyreneAngewandte Chemie International Edition, 2017
- Gold Nanoclusters Promote Electrocatalytic Water Oxidation at the Nanocluster/CoSe2 InterfaceJournal of the American Chemical Society, 2017
- Experimental and Mechanistic Understanding of Aldehyde Hydrogenation Using Au25 Nanoclusters with Lewis Acids: Unique Sites for Catalytic ReactionsJournal of the American Chemical Society, 2015
- Papain-templated Cu nanoclusters: assaying and exhibiting dramatic antibacterial activity cooperating with H2O2Nanoscale, 2015
- Significantly shorter Fe–S bond in cytochrome P450-I is consistent with greater reactivity relative to chloroperoxidaseNature Chemistry, 2015
- Intrinsic peroxidase-like activity of ferromagnetic nanoparticlesNature Nanotechnology, 2007
- Probing Structure-Function Relations in Heme-Containing Oxygenases and PeroxidasesScience, 1988