Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia
- 3 June 2021
- journal article
- research article
- Published by Elsevier in Current Biology
- Vol. 31 (14) , 3098-3114.e7
Abstract
No abstract availableKeywords
Funding Information
- National Institutes of Health (1R01NS100531, 1R01NS103481, 1R01NS111776, ZIA NS002946, ZIA NS003029)
- National Institute of Neurological Disorders and Stroke (1R01NS100531, 1R01NS103481, 1R01NS111776, ZIA NS002946, ZIA NS003029)
This publication has 77 references indexed in Scilit:
- Motile Axonal Mitochondria Contribute to the Variability of Presynaptic StrengthCell Reports, 2013
- Concepts and Methods for the Study of Axonal Regeneration in the CNSNeuron, 2012
- Spatial Parkin Translocation and Degradation of Damaged Mitochondria via Mitophagy in Live Cortical NeuronsCurrent Biology, 2012
- Identification of neuronal substrates implicates Pak5 in synaptic vesicle traffickingProceedings of the National Academy of Sciences, 2012
- Miro1 Is a Calcium Sensor for Glutamate Receptor-Dependent Localization of Mitochondria at SynapsesNeuron, 2009
- The diffusive interaction of microtubule binding proteinsCurrent Opinion in Cell Biology, 2009
- The Mechanism of Ca2+-Dependent Regulation of Kinesin-Mediated Mitochondrial MotilityCell, 2009
- Axonal growth therapeutics: regeneration or sprouting or plasticity?Trends in Neurosciences, 2008
- Docking of Axonal Mitochondria by Syntaphilin Controls Their Mobility and Affects Short-Term FacilitationCell, 2008
- Crystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKsStructure, 2007