Narcissism is defined by an inflated sense of self-importance and entitlement and can be characterized into two subtypes: grandiose narcissism and vulnerable narcissism. Both subtypes share overlapping core features of disregard for others, self-centredness and entitlement. Entitlement can lead to unrealistic expectations from others, leading people with higher narcissism to engage in maladaptive strategies (e.g., attacking others) to re-establish their desired sense of superiority and protect themselves from vulnerability. People with higher narcissism also show minimal to no concern regarding others’ well-being in various health-related situations. During the COVID-19 pandemic, individuals higher in narcissism were less likely to follow government-mandated public health interventions (e.g., mask-wearing, social distancing, isolation) and more likely to hold anti-vaccination attitudes. Sex differences indicated that males showed greater levels of non-adherence in comparison to females. Non-adherence to these public health measures is a risk factor during global pandemics, as the likelihood of disease transmission is increased.