Amino acid metabolic reprogramming in clear cell renal cell carcinoma: Pathogenic mechanisms and therapeutic targeting
- 4 January 2026
- journal article
- review article
- Published by Elsevier in Cancer Letters
- Vol. 640, 218244
Abstract
No abstract availableKeywords
Funding Information
- National Natural Science Foundation of China (82172920)
- Science and Technology Commission of Shanghai Municipality
- Science and Technology Innovation Plan Of Shanghai Science and Technology Commission (23YF1433800)
This publication has 137 references indexed in Scilit:
- The Mechanism of TRIM21 Inhibiting the Invasion and Migration of ccRCC by Stabilizing ASS1Molecular Carcinogenesis, 2024
- Efficacy and Safety of Telaglenastat Plus Cabozantinib vs Placebo Plus Cabozantinib in Patients With Advanced Renal Cell CarcinomaJAMA Oncology, 2022
- The multiple roles and therapeutic potential of HSP60 in cancerBiochemical Pharmacology, 2022
- Structure, biochemistry, and gene expression patterns of the proline biosynthetic enzyme pyrroline-5-carboxylate reductase (PYCR), an emerging cancer therapy targetAmino Acids, 2021
- Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of non‐ketotic hyperglycinemiaJournal of Inherited Metabolic Disease, 2020
- The PHGDH enigma: Do cancer cells only need serine or also a redox modulator?Cancer Letters, 2020
- Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastomaCellular and Molecular Life Sciences, 2020
- A Phase I New Approaches to Neuroblastoma Therapy Study of Buthionine Sulfoximine and Melphalan With Autologous Stem Cells for Recurrent/Refractory High-Risk NeuroblastomaPediatric Blood & Cancer, 2016
- Dose-escalation study for the targeting of CD44v+ cancer stem cells by sulfasalazine in patients with advanced gastric cancer (EPOC1205)Gastric Cancer, 2016
- Renal cell carcinoma does not express argininosuccinate synthetase and is highly sensitive to arginine deprivationviaarginine deiminaseInternational Journal of Cancer, 2006