Clinical Safety and Efficacy of Kanglaite®(Coix Seed Oil) Injection Combined with Chemotherapy in Treating Patients with Gastric Cancer
Authors:
- Xin-En HuangXHXin-En Huang
- Jie CaoJCJie Cao
- Yan-Yan LuYLYan-Yan Lu
- Xue-Yan WuXWXue-Yan Wu
- Jin LiuJLJin Liu
- Xia XuXXXia Xu
- Jin XiangJXJin Xiang
- Li-Hong YeLYLi-Hong Ye
Open Access
- 31 October 2012
- journal article
- research article
- Published by Asian Pacific Organization for Cancer Prevention in Asian Pacific Journal of Cancer Prevention
- Vol. 13 (10) , 5319-5321
Abstract
To observe efficacy and side effects, as well as the impact on quality of life, of Kanglaite® (Coix Seed Oil) injections combined with chemotherapy in the treatment of advanced gastric cancer patiensts. A consecutive cohort of 60 patients were divided into two groups:the experimental group receiving Kanglaite® Injection combined with chemotherapy and the control group with chemotherapy alone. After more than two courses of treatment, efficacy, quality of life and side effects were evaluated. The response rate and KPS score of experimental group were significantly improved as compared with those of the control group(P<0.05). In addition, gastrointestinal reactions and bone marrow suppression were significantly lower than in the control group(P<0.05). Kanglaite® Injection enhanced efficacy and reduced the side effects of chemotherapy, improving quality of life of gastric cancer patients; use of Kanglaite® injections deserves to be further investigated in randomized control clinical trails.Keywords
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