Active hematopoiesis triggers exosomal release of PRDX2 that promotes osteoclast formation
Open Access
- 15 February 2021
- journal article
- research article
- Published by Wiley in Physiological Reports
- Vol. 9 (3) , e14745
Abstract
Increased bone marrow erythropoiesis secondary to anemia leads to upregulation of PRDX2, which is released in the exosomes and acts to induce osteoclast formation. Increased bone resorption by the os...Keywords
Funding Information
- Canadian Institutes of Health Research (MOP‐77643, PJT‐165939)
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