Number and Brightness analysis of alpha-synuclein oligomerization and the associated mitochondrial morphology alterations in live cells
Open Access
- 1 June 2014
- journal article
- Published by Elsevier in Biochimica et Biophysica Acta (BBA) - General Subjects
- Vol. 1840 (6) , 2014-2024
Abstract
No abstract availableKeywords
Funding Information
- Fondazione Ing. Aldo Gini
- NIH (P41 P41-RRO3155, P41 GM103540, P50-GM076516)
This publication has 64 references indexed in Scilit:
- Protein degradation pathways in Parkinson’s disease: curse or blessingActa Neuropathologica, 2012
- Alpha-synuclein aggregation involves a bafilomycin A1-sensitive autophagy pathwayAutophagy, 2012
- The Mitochondrial Chaperone Protein TRAP1 Mitigates α-Synuclein ToxicityPLOS Genetics, 2012
- In vivo demonstration that α-synuclein oligomers are toxicProceedings of the National Academy of Sciences, 2011
- α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in VitroScience, 2010
- Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cellsProceedings of the National Academy of Sciences, 2009
- Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease BrainJournal of Biological Chemistry, 2008
- Detection of novel intracellular O‐synuclein oligomeric species by fluorescence lifetime imagingThe FASEB Journal, 2006
- α-Synuclein, Especially the Parkinson's Disease-associated Mutants, Forms Pore-like Annular and Tubular ProtofibrilsJournal of Molecular Biology, 2002
- Dopamine-dependent neurotoxicity of α-synuclein: A mechanism for selective neurodegeneration in Parkinson diseaseNature Medicine, 2002