Pyruvate Dehydrogenase Kinase Protects Dopaminergic Neurons from Oxidative Stress in Drosophila DJ-1 Null Mutants
Open Access
- 21 April 2022
- journal article
- research article
- Published by Elsevier in Molecules and Cells
- Vol. 45 (7) , 454-464
Abstract
Yoonjeong Lee, Jaehyeon Kim, Hyunjin Kim, Ji Eun Han, Sohee Kim, Kyong-hwa Kang, Donghoon Kim, Jong-Min Kim, and Hyongjong Koh. Mol. Cells 2022;45:454-64. https://doi.org/10.14348/molcells.2022.5002Keywords
This publication has 41 references indexed in Scilit:
- Neuroprotective Function of DJ-1 in Parkinson’s DiseaseOxidative Medicine and Cellular Longevity, 2013
- Drosophila DJ-1 Decreases Neural Sensitivity to Stress by Negatively Regulating Daxx-Like Protein through dFOXOPLOS Genetics, 2013
- Pyruvate Dehydrogenase Kinases in the Nervous System: Their Principal Functions in Neuronal-glial Metabolic Interaction and Neuro-metabolic DisordersCurrent Neuropharmacology, 2012
- Human neuronal uncoupling proteins 4 and 5 (UCP4 and UCP5): structural properties, regulation, and physiological role in protection against oxidative stress and mitochondrial dysfunctionBrain and Behavior, 2012
- Phosphorylation status of pyruvate dehydrogenase distinguishes metabolic phenotypes of cultured rat brain astrocytes and neuronsGlia, 2010
- DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responsesProceedings of the National Academy of Sciences, 2009
- DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2Proceedings of the National Academy of Sciences, 2006
- Mechanism of regulation of the hypoxia‐inducible factor‐1α by the von Hippel‐Lindau tumor suppressor proteinThe EMBO Journal, 2000
- DJ-1, a Novel Oncogene Which Transforms Mouse NIH3T3 Cells in Cooperation withrasBiochemical and Biophysical Research Communications, 1997
- Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1Journal of Biological Chemistry, 1996