Molecular study of 45,X conceptuses: Correlation with clinical findings
Authors:
- 15 February 1992
- journal article
- research article
- Published by Wiley in American Journal of Medical Genetics
- Vol. 42 (4) , 487-490
Abstract
The parental origin of the single X in 45 cases (40 liveborns and 5 fetuses) with a 45, X karyo‐type was studied using polymorphic DNA probes. The single X was paternal in origin (Xp) in 10 cases (22.2%) and maternal (Xm) in 35 cases (77.8%). Y chromosome material was detected in 1 out of the 35 cases with a 45, Xm constitution. Analysis of parental ages and clinical data of the patients with respect to the origin of the single X revealed no significant differences between the origins.Keywords
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