Prognostic value of chronic obstructive pulmonary disease in coronary artery bypass grafting☆

Authors:
  • JAJosé A. Montero Argudo
    José A. Montero Argudo
  • OAOscar Gil Albarova
    Oscar Gil Albarova
  • FSFernando Hornero Sos
    Fernando Hornero Sos
  • SLSergio Cánovas López
    Sergio Cánovas López
  • MCMaría Bueno Codoñer
    María Bueno Codoñer
  • JMJosé A. Buendía Miñano
    José A. Buendía Miñano
  • IAIgnacio Rodríguez Albarran
    Ignacio Rodríguez Albarran
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Abstract
Coronary and chronic lung diseases have become a common association. This comorbidity has been generically considered by most of the operative risk scores, but its functional severity has seldom been addressed by these models. Our objective was to analyze its prognostic relevance considering preoperative pulmonary function parameters. All patients undergoing CABG from May 1993 to December 2004 have been reviewed. One thousand four hundred and twelve patients with preoperative pulmonary function test were finally included in the study. Obstructive lung disease was defined when FEV1/FVC80%, 0.4% in FEV1: 60-80%, 10.8% in FEV1: 40-59% and 54% in FEV1: 60%: 24.6% versus 1.4% (p<0.001). Chronic obstructive lung disease was not an independent predictor of mortality but FEV1< or =60% was significantly associated with death. This study on chronic lung comorbidity in CABG patients shows that this association can be of deleterious prognostic value but this effect is directly related to the degree of functional severity. Preoperative FEV1<60% must be considered as a primary prognostic factor in patients undergoing CABG procedures.