Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis
Authors:
Open Access
- 1 November 2019
- journal article
- research article
- Published by Elsevier in Cell Reports
- Vol. 29 (6) , 1482-1498.e4
Abstract
No abstract availableKeywords
Funding Information
- Major State Basic Research Development Program of China (2016YFA0102400)
- National Natural Science Foundation of China (81773017, 41931291, 81502446)
This publication has 48 references indexed in Scilit:
- TTK/hMPS1 Is an Attractive Therapeutic Target for Triple-Negative Breast CancerPLOS ONE, 2013
- Smurf2‐mediated degradation of EZH2 enhances neuron differentiation and improves functional recovery after ischaemic strokeEMBO Molecular Medicine, 2013
- Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organizationGenes & Development, 2012
- EZH2-Mediated Concordant Repression of Wnt Antagonists Promotes β-Catenin–Dependent HepatocarcinogenesisCancer Research, 2011
- Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylationBlood, 2011
- Methylation of the Retinoblastoma Tumor Suppressor by SMYD2Journal of Biological Chemistry, 2010
- Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center originNature Genetics, 2010
- SIAH1 induced apoptosis by activation of the JNK pathway and inhibited invasion by inactivation of the ERK pathway in breast cancer cellsCancer Science, 2009
- LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast CancerCell, 2009
- Structural Analysis of Siah1-Siah-interacting Protein Interactions and Insights into the Assembly of an E3 Ligase Multiprotein ComplexJournal of Biological Chemistry, 2005