Outcome of transoral laser microsurgery for T2‐T3 tumors growing in the laryngeal anterior commissure

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Abstract
Background: To evaluate the outcomes of transoral laser microsurgery (TLM) in the treatment of T2 to T3 laryngeal carcinomas growing in the laryngeal anterior commissure.Methods: This study was a retrospective analysis of 107 patients. Overall survival, disease‐specific survival, and laryngectomy‐free survival were analyzed. Technical difficulties, postoperative complications, influence of the learning curve, and the number of surgeries were evaluated.Results: Five‐year overall survival, disease‐specific survival, and laryngectomy‐free survival were 71%, 79.5%, and 71.4%, respectively. The probability of tumor relapse was related to the status of the margins (p = .01) and to surgical experience (p = .02), but not to tumor exposure (p = .78) or pT category (p = .36). Disease‐specific survival differed significantly between the group of patients treated in the early period of surgical experience and those treated in the advanced period of surgical experience (71% vs 94%; p = .02)Conclusion: TLM is a useful treatment for T2 to T3 laryngeal carcinomas growing in the laryngeal anterior commissure when it is performed under an advanced learning curve. © 2010 Wiley Periodicals, Inc. Head Neck, 2010

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