Palladium-catalyzed hydrofunctionalization cyclization of 1,3-enynes to access cyclopenta[ b ]indoles
Open Access
- 9 March 2026
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Organic Chemistry Frontiers
- Vol. 13 (9) , 2768-2774
Abstract
A palladium-catalyzed sequential hydroarylation and hydroalkylation of 1,3-enynes was developed, providing efficient access to cyclopenta[ b ]indoles and their derivatives in good yields with excellent chemoselectivities.Keywords
Funding Information
- National Natural Science Foundation of China (NSFC 22371299)
- Natural Science Foundation of Jiangsu Province (BK20242068)
- State Key Laboratory of Natural Medicines (SKLNMZZ202211)
- State Key Laboratory of Natural Medicines (SKLNMKF202401)
This publication has 69 references indexed in Scilit:
- Cobalt‐Catalyzed Asymmetric Alkylation of (Hetero)Arenes with StyrenesAngewandte Chemie International Edition, 2022
- Enantioselective Palladium‐Catalyzed Hydrophosphinylation of Allenes with Phosphine Oxides: Access to Chiral Allylic Phosphine OxidesAngewandte Chemie International Edition, 2021
- Enantioselective Addition of Pyrazoles to Dienes**Angewandte Chemie International Edition, 2021
- Asymmetric Alkoxy‐ and Hydroxy‐Carbonylations of Functionalized Alkenes Assisted by β‐Carbonyl GroupsAngewandte Chemie International Edition, 2021
- Palladium‐Catalyzed Intramolecular Trost–Oppolzer‐Type Alder–Ene Reaction of Dienyl Acetates to CyclopentadienesAngewandte Chemie International Edition, 2018
- Asymmetric Dearomatization of Indoles through a Michael/Friedel–Crafts‐Type Cascade To Construct Polycyclic SpiroindolinesAngewandte Chemie International Edition, 2015
- Experimental and Computational Study of the Catalytic Asymmetric 4π‐Electrocyclization of N‐HeterocyclesAngewandte Chemie International Edition, 2014
- Multistep One‐Pot Synthesis of Enantioenriched Polysubstituted Cyclopenta[b]indolesAngewandte Chemie International Edition, 2011
- Lewis Acid Catalyzed Intramolecular Direct Ene Reaction of IndolesAngewandte Chemie International Edition, 2010
- Fischer Indole Synthesis with Organozinc ReagentsAngewandte Chemie International Edition, 2010