Efficacy and safety of zapnometinib in hospitalised adult patients with COVID-19 (RESPIRE): a randomised, double-blind, placebo-controlled, multicentre, proof-of-concept, phase 2 trial
Open Access
- 4 October 2023
- journal article
- research article
- Published by Elsevier in eClinicalMedicine
- Vol. 65, 102237
Abstract
No abstract availableKeywords
Funding Information
- Bundesministerium für Forschung, Technologie und Raumfahrt
- BMBF Berlin
This publication has 25 references indexed in Scilit:
- A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19New England Journal of Medicine, 2020
- Inflammatory side effects of BRAF and MEK inhibitorsMelanoma Research, 2019
- Cardiovascular Adverse Events Associated With BRAF and MEK InhibitorsJAMA Network Open, 2019
- OCULAR ADVERSE EVENTS ASSOCIATED WITH MEK INHIBITORSRetina, 2019
- Comparison of antiviral resistance across acute and chronic viral infectionsAntiviral Research, 2018
- The MEK-inhibitor CI-1040 displays a broad anti-influenza virus activity in vitro and provides a prolonged treatment window compared to standard of care in vivoAntiviral Research, 2017
- MEK inhibitors: a new class of chemotherapeutic agents with ocular toxicityEye, 2015
- Inhibition of influenza virus-induced NF-kappaB and Raf/MEK/ERK activation can reduce both virus titers and cytokine expression simultaneously in vitro and in vivoAntiviral Research, 2011
- RNA viruses and the mitogenic Raf/MEK/ERK signal transduction cascadeBiological Chemistry, 2008
- Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascadeNature Cell Biology, 2001