Supplementary Methods, Figures 1 - 9 from AIP1 Expression in Tumor Niche Suppresses Tumor Progression and Metastasis

Authors:
  • WJWeidong Ji
    Weidong Ji
  • YLYonghao Li
    Yonghao Li
  • YHYun He
    Yun He
  • MYMingzhu Yin
    Mingzhu Yin
  • HZHuanjiao Jenny Zhou
    Huanjiao Jenny Zhou
  • TBTitus J. Boggon
    Titus J. Boggon
  • HZHaifeng Zhang
    Haifeng Zhang
  • WMWang Min
    Wang Min
Open Access
Publisher website
Google Scholar
Abstract
Supplementary Figure S1-S9 - qRT-PCR for AIP1 expression in vascular EC but not in TAMs (S1); Examination of tumor growth and metastasis of orthotopic breast cancer model in AIP1-deficient mice (S2); Elucidation of potential steps prior to extravasation regulated by AIP1 during tumor metastasis (S3); Examination of tumor lymphangiogenesis in AIP1-deficient mice (S4); Measurement of gene expression of pre-niche markers at the lung of AIP1-deficient mice (S5); Effects of VEGFR2 inhibitors on tumor angiogenesis, pre-metastatic niche formation and tumor metastasis (S6); Measurement of tumor cell EMT in AIP1-deficient environment (S7); Examination of AIP1-VEGFR2 signaling in tumor cell EMT program (S8); Measurement of EC proliferation and EC apoptosis in primary tumor and lung tissue of AIP1-deficient mice (S9).