Neutrophils: Their Role in the Formation of a Tick Feeding Lesion

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Abstract
Dogs infested with adult Rhipicephalus sanguineus were given nitrogen mustard to reduce leukocyte numbers. In the treated animals the tick lesions were insignificant, lacking the collagen destruction found in untreated hosts, but the ticks engorged normally. Feeding results from tick secretions causing vascular trauma and is independent of tissue damage associated with inflammatory responses.