Diagnostic Relevance of β2-Transferrin for the Detection of Cerebrospinal Fluid Fistulas
Authors:
- Thomas AverbeckTAThomas Averbeck
- Ulrich WursterUWUlrich Wurster
- Meike HarmeningMHMeike Harmening
- Thomas LenarzTLThomas Lenarz
- Timo StöverTSTimo Stöver
Open Access
- 1 October 2004
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery
- Vol. 130 (10) , 1178-1184
Abstract
Cerebrospinal fluid (CSF) fistulas can become a life-threatening condition. These occur following a penetrating injury of the leptomeninges, dura, and bone, resulting in an extracranial discharge of CSF and providing an entry for pathogens into the subarachnoid space, potentially leading to meningitis. Therefore, early diagnosis of a CSF leak in patients with rhinorrhea or otorrhea of uncertain origin is essential.Keywords
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