Supplementary Figure 3 from Progression of EGFR-Mutant Lung Adenocarcinoma is Driven By Alveolar Macrophages

Authors:
  • DWDon-Hong Wang
    Don-Hong Wang
  • HLHyun-Sung Lee
    Hyun-Sung Lee
  • DYDavid Yoon
    David Yoon
  • GBGerald Berry
    Gerald Berry
  • TWThomas M. Wheeler
    Thomas M. Wheeler
  • DSDavid J. Sugarbaker
    David J. Sugarbaker
  • FKFarrah Kheradmand
    Farrah Kheradmand
  • EEEdgar Engleman
    Edgar Engleman
  • BBBryan M. Burt
    Bryan M. Burt

Abstract
CD45-humanEGFR+ cells were sorted from the lungs of bitransgenic mice fed dox for 7 weeks and cultured for 24 hours in the presence of empty liposomes or clodronate-liposomes. Flow cytometry was used to evaluate cell death (DAPI) and apoptosis (Annexin V).