Institution-wide and Within-Patient Evolution of Daptomycin Susceptibility in Vancomycin-Resistant Enterococcus faecium Bloodstream Infections
Authors:
- 14 January 2018
- journal article
- editorial
- Published by Cambridge University Press (CUP) in Infection Control & Hospital Epidemiology
- Vol. 39 (2) , 226-228
Abstract
We report daptomycin minimum inhibitory concentrations (MICs) for vancomycin-resistant Enterococcus faecium isolated from bloodstream infections over a 4-year period. The daptomycin MIC increased over time hospital-wide for initial isolates and increased over time within patients, culminating in 40% of patients having daptomycin-nonsusceptible isolates in the final year of the study.Infect Control Hosp Epidemiol 2018;39:226–228Keywords
This publication has 10 references indexed in Scilit:
- Resurrecting the intestinal microbiota to combat antibiotic-resistant pathogensScience, 2016
- Influence of Minimum Inhibitory Concentration in Clinical Outcomes ofEnterococcus faeciumBacteremia Treated With Daptomycin: Is it Time to Change the Breakpoint?Clinical Infectious Diseases, 2016
- Does High-Dose Antimicrobial Chemotherapy Prevent the Evolution of Resistance?PLOS Computational Biology, 2016
- Emergence of daptomycin non-susceptibility in colonizing vancomycin-resistant Enterococcus faecium isolates during daptomycin therapyInternational Journal of Medical Microbiology, 2015
- Identification of a Novel Clone, ST736, among Enterococcus faecium Clinical Isolates and Its Association with Daptomycin NonsusceptibilityAntimicrobial Agents and Chemotherapy, 2014
- Epidemiology of Vancomycin-Resistant Enterococci with Reduced Susceptibility to DaptomycinInfection Control & Hospital Epidemiology, 2012
- Correlation between Mutations in liaFSR of Enterococcus faecium and MIC of Daptomycin: Revisiting Daptomycin BreakpointsAntimicrobial Agents and Chemotherapy, 2012
- Daptomycin exposure precedes infection and/or colonization with daptomycin non-susceptible enterococcusAntimicrobial Resistance & Infection Control, 2012
- Emergence of Daptomycin-Resistant VRE: Experience of a Single InstitutionInfection Control & Hospital Epidemiology, 2011
- The epidemiology of antibiotic resistance in hospitals: Paradoxes and prescriptionsProceedings of the National Academy of Sciences, 2000