Development of an α′-hydroxy enone for the aminocatalytic asymmetric formal conjugate addition of aldehydes to acrylates, vinyl ketones and acrolein

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Abstract
Formally, a unified enantioselective conjugate addition of aldehydes to acrolein, alkyl–vinyl ketones and acrylic esters is feasible using simple commercially available aminocatalysts and α′-hydroxy enones as self-activated acceptor templates.
Funding Information
  • Gobierno de Navarra (34E/2020)
  • Eusko Jaurlaritza (IT1583-22)
  • Ministerio de Ciencia e Innovación (PID2019-109633GB/AEI/10.13039/501100011033)

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