Self-reported health literacy and medication adherence in older adults: a systematic review
Open Access
Abstract
Objectives To give an overview over the associations between self-reported health literacy and medication adherence in older adults. Design A systematic literature review of quantitative studies published in English and German. Data sources MEDLINE via PubMed, CINAHL, Cochrane Library, Epistemonikos and LIVIVO were searched. Eligibility criteria Included studies had to examine the associations between self-reported health literacy and medication adherence in the elderly (samples including ≥66% of ≥60 years old) and had to use a quantitative methodology and had to be written in English or German. Data extraction and synthesis All studies were screened for inclusion criteria by two independent reviewers. A narrative synthesis was applied to analyse all included studies thematically. Quality assessment was conducted using the NIH Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. Results We found 2313 studies, of which nine publications from eight studies were included in this review. Five studies reported a majority of participants with limited health literacy, one study reported a majority of participants with adequate health literacy, and three publications from two studies only reported mean levels of health literacy. Eight publications from seven studies used self-reports to measure medication adherence, while one study used the medication possession ratio. Overall, six publications from five studies reported significantly positive associations between health literacy and medication adherence while two studies reported positive but non-significant associations between both constructs and one study reported mixed results. Conclusion In this review, associations between self-reported health literacy and medication adherence are rather consistent, indicating positive associations between both constructs in older adults. However, concepts and measures of health literacy and medication adherence applied in the included studies still show a noteworthy amount of heterogeneity (eg, different use of cutoffs). These results reveal the need for more differentiated research in this area. PROSPERO registration number CRD42019141028.Keywords
This publication has 55 references indexed in Scilit:
- Measuring health literacy in populations: illuminating the design and development process of the European Health Literacy Survey Questionnaire (HLS-EU-Q)BMC Public Health, 2013
- Predictors of Medication Adherence in Elderly Patients with Chronic Diseases Using Support Vector Machine ModelsHealthcare Informatics Research, 2013
- The Economic Burden of Inappropriate Drug Prescribing, Lack of Adherence and Compliance, Adverse Drug Events in Older PeopleDrug Safety, 2012
- Relationship of Health Literacy to Intentional and Unintentional Non-Adherence of Hospital Discharge MedicationsJournal of General Internal Medicine, 2011
- Low Health Literacy and Health Outcomes: An Updated Systematic ReviewAnnals of Internal Medicine, 2011
- Association of age, health literacy, and medication management strategies with cardiovascular medication adherencePatient Education and Counseling, 2010
- Validation of Screening Questions for Limited Health Literacy in a Large VA Outpatient PopulationJournal of General Internal Medicine, 2008
- Literacy, self-efficacy, and HIV medication adherencePatient Education and Counseling, 2007
- Health literacy and anticoagulation-related outcomes among patients taking warfarinJournal of General Internal Medicine, 2006
- Concurrent and Predictive Validity of a Self-reported Measure of Medication AdherenceMedical Care, 1986