Genetic Susceptibility to Diclofenac-Induced Hepatotoxicity: Contribution of UGT2B7, CYP2C8, and ABCC2 Genotypes
Authors:
- Ann K. DalyADAnn K. Daly
- Guruprasad P. AithalGAGuruprasad P. Aithal
- Julian B.S. LeathartJLJulian B.S. Leathart
- Richard A. SwainsburyRSRichard A. Swainsbury
- Tarana Singh DangTDTarana Singh Dang
- Christopher P. DayCDChristopher P. Day
- 1 January 2007
- journal article
- Published by Elsevier in Gastroenterology
- Vol. 132 (1) , 272-281
Abstract
No abstract availableKeywords
This publication has 45 references indexed in Scilit:
- Drug-Induced Liver Injury: An Analysis of 461 Incidences Submitted to the Spanish Registry Over a 10-Year PeriodGastroenterology, 2005
- Outcome and prognostic markers in severe drug‐induced liver disease†Hepatology, 2005
- Fulminant drug-induced hepatic failure leading to death or liver transplantation in SwedenScandinavian Journal of Gastroenterology, 2005
- Acute and clinically relevant drug‐induced liver injury: a population based case‐control studyBritish Journal of Clinical Pharmacology, 2004
- Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicityToxicology and Applied Pharmacology, 2003
- The Metabolism of Diclofenac - Enzymology and Toxicology PerspectivesCurrent Drug Metabolism, 2003
- Prospective surveillance of acute serious liver disease unrelated to infectious, obstructive, or metabolic diseases: epidemiological and clinical features, and exposure to drugsJournal of Hepatology, 2002
- Comparison of Two Clinical Scales for Causality Assessment in HepatotoxicityHepatology, 2001
- Relationship of polymorphism in CYP2C9 to genetic susceptibility to diclofenac-induced hepatitisPharmacogenetics, 2000
- Idiosyncratic Liver Toxicity of Nonsteroidal Antiinflammatory Drugs: Molecular Mechanisms and PathologyCritical Reviews in Toxicology, 1995