A Gene Expressed in the Endoderm of the Sea Urchin Embryo

Authors:
  • RLRichard Lum
    Richard Lum
  • THTom Humphreys
    Tom Humphreys
Publisher website
Google Scholar
Abstract
Using a previously cloned, developmentally regulated mRNA sequence expressed predominantly in the endoderm of sea urchin pluteus larvae, we isolated genomic clones and additional cDNA clones to define the gene and the protein it encodes. Nucleic acid sequencing revealed that the gene consists of four exons interrupted by three introns and spans approximately 3600 bp. It encodes a low-molecular-weight protein with polar ends. A stretch of Glu and Asp residues at its carboxyl terminus suggests that it is a nucleic acid-binding protein and a stretch of four Lys residues near the amino terminus suggests a nuclear localization signal.

This publication has 25 references indexed in Scilit: