Metformin has direct effects on human ovarian steroidogenesis

This publication has 31 references indexed in Scilit:

• Ovarian steroidogenic response to human chorionic gonadotrophin in obese women with polycystic ovary syndrome: effect of metformin
  Human Reproduction, 2001
• Thiazolidinediones but Not Metformin Directly Inhibit the Steroidogenic Enzymes P450c17 and 3β-Hydroxysteroid Dehydrogenase
  Journal of Biological Chemistry, 2001
• Effects of the insulin sensitizing drug metformin on ovarian function, follicular growth and ovulation rate in obese women with oligomenorrhoea
  Human Reproduction, 1999
• Evidence for a primary abnormality of thecal cell steroidogenesis in the polycystic ovary syndrome
  Clinical Endocrinology, 1997
• Decreases in Ovarian Cytochrome P450c17α Activity and Serum Free Testosterone after Reduction of Insulin Secretion in Polycystic Ovary Syndrome
  New England Journal of Medicine, 1996
• Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia, and systolic blood pressure, while facilitating normal menses and pregnancy
  Metabolism, 1994
• Prostaglandin F2α activates protein kinase C in human ovarian cells
  Molecular and Cellular Endocrinology, 1993
• Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome
  Clinical Endocrinology, 1992
• INHIBITION OF OESTRADIOL PRODUCTION BY EPIDERMAL GROWTH FACTOR IN HUMAN GRANULOSA CELLS OF NORMAL AND POLYCYSTIC OVARIES
  Clinical Endocrinology, 1990
• HETEROGENEITY OF THE POLYCYSTIC OVARY SYNDROME: CLINICAL, ENDOCRINE AND ULTRASOUND FEATURES IN 556 PATIENTS
  Clinical Endocrinology, 1989