B Cell-Targeted Polylactic Acid Nanoparticles as Platform for Encapsulating Jakinibs: Potential Therapeutic Strategy for Systemic Lupus Erythematosus
- 1 November 2023
- journal article
- research article
- Published by Taylor & Francis in Nanomedicine
- Vol. 18 (27) , 2001-2019
Abstract
Background: B cells are pivotal in systemic lupus erythematosus and autoimmune disease pathogenesis. Materials & methods: To address this, Nile Red-labeled polylactic acid nanoparticles (NR-PLA NPs... Plain language summary In this study, a new approach to treating autoimmune diseases, particularly systemic lupus erythematosus, was investigated by focusing on a type of immune cell called B cells...Keywords
Funding Information
- Minciencias (111584467267 -925-2019)
This publication has 59 references indexed in Scilit:
- Bruton’s Tyrosine Kinase Mediates the Synergistic Signalling between TLR9 and the B Cell Receptor by Regulating Calcium and CalmodulinPLOS ONE, 2013
- Janus kinase inhibitors in autoimmune diseasesAnnals of the Rheumatic Diseases, 2013
- Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus in miceJournal of Clinical Investigation, 2013
- Folate‐targeted nanoparticles show efficacy in the treatment of inflammatory arthritisArthritis & Rheumatism, 2011
- Biodegradable nanoparticles are excellent vehicle for site directed in-vivo delivery of drugs and vaccinesJournal of Nanobiotechnology, 2011
- Interleukin 4 and STAT6 gene polymorphisms are associated with systemic lupus erythematosus in Chinese patientsLupus, 2010
- The role of B cells in lupus pathogenesisThe International Journal of Biochemistry & Cell Biology, 2010
- IL-21 regulates germinal center B cell differentiation and proliferation through a B cell–intrinsic mechanismJournal of Experimental Medicine, 2010
- Somatic Mutations of JAK1 and JAK3 in Acute Leukemias and Solid CancersClinical Cancer Research, 2008
- STAT4and the Risk of Rheumatoid Arthritis and Systemic Lupus ErythematosusNew England Journal of Medicine, 2007