Cardiac Output is a Determinant of the Initial Concentrations of Propofol After Short-Infusion Administration

Authors:
  • RURichard N. Upton
    Richard N. Upton
  • GLGuy L. Ludbrook
    Guy L. Ludbrook
  • CGCliff Grant
    Cliff Grant
  • AMAllison M. Martinez
    Allison M. Martinez

Abstract
The initial arterial concentrations of propofol after IV administration were shown to be inversely related to cardiac output. This implies that cardiac output may be a determinant of the induction of anesthesia with propofol.

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