Towards appropriate polypharmacy in older cardiovascular patients: How many medications do I have to take?
Open Access
- 11 December 2019
- journal article
- review article
- Published by Wiley in Clinical Cardiology
- Vol. 43 (2) , 137-144
Abstract
Background: Polypharmacy in older adults leads to increased risks of side effects and drug‐drug interactions, affecting their health outcomes and quality of life. Deprescribing, the act of simplifying medication regimens, is challenging due to the lack of consensus guidelines.Hypothesis: To offer some guidance on managing medication regimens for older cardiovascular patients.Methods: We reviewed the most recent pertinent guidelines and literature.Results: This review provides practical considerations for appropriate prescribing in the older population with cardiovascular disease in order to strike a balance between unnecessary or harmful medications and therapies with proven long‐term benefits.Conclusion: On‐going dialogue between healthcare providers and patients allows close monitoring of medication effectiveness and prevention of side effects. Medication regimens require individualization, as patients' goals of care change with advancing age.Keywords
This publication has 41 references indexed in Scilit:
- Relation of Digoxin Use in Atrial Fibrillation and the Risk of All-Cause Mortality in Patients ≥65 Years of Age With Versus Without Heart FailureThe American Journal of Cardiology, 2014
- 2013 ACCF/AHA Guideline for the Management of Heart FailureJACC, 2013
- Use of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous coronary intervention: an open-label, randomised, controlled trialThe Lancet, 2013
- AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients With Coronary and Other Atherosclerotic Vascular Disease: 2011 UpdateCirculation, 2011
- A Novel User-Friendly Score (HAS-BLED) To Assess 1-Year Risk of Major Bleeding in Patients With Atrial FibrillationChest, 2010
- Refining Clinical Risk Stratification for Predicting Stroke and Thromboembolism in Atrial Fibrillation Using a Novel Risk Factor-Based ApproachChest, 2010
- Incidence of Death and Acute Myocardial Infarction Associated With Stopping Clopidogrel After Acute Coronary SyndromeJAMA, 2008
- Aging Biology and Geriatric Clinical PharmacologyPharmacological Reviews, 2004
- The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) studyJACC, 2004
- A Comparison of Rate Control and Rhythm Control in Patients with Atrial FibrillationNew England Journal of Medicine, 2002