Pentamethylphenyl (Ph*) and Related Derivatives as Useful Acyl Protecting Groups for Organic Synthesis: A Preliminary Study

Authors:
Publisher website
Google Scholar
Abstract
A study of acyl protecting groups derived from the Ph* motif is reported. While initial studies indicated that a variety of functional groups were not compatible with the Br2-mediated cleavage conditions required to release the Ph* group, strategies involving the use of different reagents or a modification of Ph* itself (Ph*OH) were investigated to solve this problem. Received: 13 July 2020 Accepted after revision: 31 August 2020 Publication Date: 22 September 2020 (online) © 2020. Thieme. All rights reserved Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany
Funding Information
  • Agency for Science, Technology and Research
  • Engineering and Physical Sciences Research Council (EP/L023121/1)