Zidovudine and the Natural History of the Acquired Immunodeficiency Syndrome

Authors:
  • JHJulia Hidalgo
    Julia Hidalgo
  • BSBarbara W. Sugland
    Barbara W. Sugland
  • RCRichard E. Chaisson
    Richard E. Chaisson

Abstract
We sought to describe the trends in survival from 1983 to 1989 among persons with the acquired immunodeficiency syndrome (AIDS) and to examine the relative effects on the natural history of AIDS of zidovudine use and demographic and clinical characteristics. This longitudinal, observational, population-based study used data from the Maryland Human Immunodeficiency Virus Information System, a data base that links information from the Maryland AIDS Registry with data on public and private health care claims, vital statistics, and hospital, long-term care, and ambulatory care records.

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