Epigenetic regulators of neuronal ferroptosis identify novel therapeutics for neurological diseases: HDACs, transglutaminases, and HIF prolyl hydroxylases
Authors:
Open Access
- 28 October 2020
- journal article
- review article
- Published by Elsevier in Neurobiology of Disease
- Vol. 147, 105145
Abstract
No abstract availableKeywords
Funding Information
- Dr. Miriam and Sheldon G. Adelson Medical Research Foundation
- National Institute on Aging
This publication has 61 references indexed in Scilit:
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell DeathCell, 2012
- Activation of the HIF Prolyl Hydroxylase by the Iron Chaperones PCBP1 and PCBP2Cell Metabolism, 2011
- Distinct Changes in cAMP and Extracellular Signal-Regulated Protein Kinase Signalling in L-DOPA-Induced DyskinesiaPLOS ONE, 2010
- Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington diseaseEMBO Molecular Medicine, 2010
- Antioxidants, HIF Prolyl Hydroxylase Inhibitors or Short Interfering RNAs to BNIP3 or PUMA, Can Prevent Prodeath Effects of the Transcriptional Activator, HIF-1α, in a Mouse Hippocampal Neuronal LineAntioxidants & Redox Signaling, 2008
- Tissue-type transglutaminase and the effects of cystamine on intracerebral hemorrhage-induced brain edema and neurological deficitsBrain Research, 2008
- ATF4 is an oxidative stress–inducible, prodeath transcription factor in neurons in vitro and in vivoJournal of Experimental Medicine, 2008
- Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase PathwayMolecular Cell, 2008
- The von Hippel-Lindau Tumor Suppressor Protein and Egl-9-Type Proline Hydroxylases Regulate the Large Subunit of RNA Polymerase II in Response to Oxidative StressMolecular and Cellular Biology, 2008
- RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channelsNature, 2007