Secreted frizzled-related protein 5 suppresses inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes through down-regulation of c-Jun N-terminal kinase
- 24 April 2014
- journal article
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 53 (9) , 1704-1711
Abstract
Objective. This study was performed to investigate the effect of secreted frizzled-related protein 5 (Sfrp5), a novel anti-inflammatory adipokine that competes with the frizzled proteins for Wnt binding, on inflammatory response and the c-Jun N-terminal kinase (JNK) signalling pathway in RA.Keywords
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