Genetic characterization of a novel picornavirus detected in Miniopterus schreibersii bats
- 1 April 2015
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 96 (4) , 815-821
Abstract
Bats are important reservoirs of many viruses with zoonotic potential worldwide, including Europe. Among bat viruses, members of the Picornaviridae family remain a neglected group. We performed viral metagenomic analyses on Miniopterus schreibersii bat fecal samples, collected in Hungary in 2013. In the present study we report the first molecular data and genomic characterization of a novel picornavirus from the bat species M. schreibersii in Europe. Based on phylogenetic analyses, the novel bat picornaviruses unambiguously belong to the Mischivirus genus and were highly divergent from other bat-derived picornaviruses of the Sapelovirus genus. Although the Hungarian viruses were most closely related to Mischivirus A, they formed a separate monophyletic branch within the genus.Keywords
This publication has 24 references indexed in Scilit:
- Identification of a Novel Picornavirus in Healthy Piglets and Seroepidemiological Evidence of Its Presence in HumansPLOS ONE, 2013
- Evasion of Antiviral Innate Immunity by Theiler's Virus L* Protein through Direct Inhibition of RNase LPLOS Pathogens, 2013
- Virome Analysis for Identification of Novel Mammalian Viruses in Bat Species from Chinese ProvincesJournal of Virology, 2012
- Complete Genome Analysis of Three Novel Picornaviruses from Diverse Bat SpeciesJournal of Virology, 2011
- Identification of a Novel Neuropathogenic Theiler's Murine Encephalomyelitis VirusJournal of Virology, 2011
- Guidelines of the American Society of Mammalogists for the use of wild mammals in researchJournal of Mammalogy, 2011
- CDD: a Conserved Domain Database for the functional annotation of proteinsNucleic Acids Research, 2010
- A highly prevalent and genetically diversified Picornaviridae genus in South Asian childrenProceedings of the National Academy of Sciences, 2008
- Phylogenetic Analysis of the SpeciesTheilovirus: Emerging Murine and Human PathogensJournal of Virology, 2008
- The immunodominant CD8+ T cell epitope region of Theiler's virus in resistant C57BL/6 mice is critical for anti-viral immune responses, viral persistence, and binding to the host cellsVirology, 2007