Animal Model for Maturity-onset Diabetes of the Young Generated by Disruption of the Mouse Glucokinase Gene
Authors:
Open Access
- 1 September 1995
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 270 (37) , 21464-21467
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- Compensation in Pancreatic β-Cell Function in Subjects With Glucokinase MutationsDiabetes, 1994
- Ribozyme-mediated attenuation of pancreatic beta-cell glucokinase expression in transgenic mice results in impaired glucose-induced insulin secretion.Proceedings of the National Academy of Sciences, 1994
- Insulin secretory abnormalities in subjects with hyperglycemia due to glucokinase mutations.Journal of Clinical Investigation, 1994
- Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships.Proceedings of the National Academy of Sciences, 1993
- Primary pancreatic beta-cell secretory defect caused by mutations in glucokinase gene in kindreds of maturity onset diabetes of the youngThe Lancet, 1992
- Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitusNature, 1992
- Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitusNature, 1992
- Glucokinase as Glucose Sensor and Metabolic Signal Generator in Pancreatic β-Cells and HepatocytesDiabetes, 1990
- Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans.Proceedings of the National Academy of Sciences, 1989
- Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genesNature, 1988