Influenza Virus Genomic Surveillance, Arizona, USA, 2023–2024
Authors:
- Rabia MaqsoodRabia Maqsood
- Matthew F. SmithMatthew F. Smith
- LaRinda A. HollandLaRinda A. Holland
- Regan A. SullinsRegan A. Sullins
- Steven C. HollandSteven C. Holland
- Michelle TanMichelle Tan
- Gabrielle M. Hernandez BarreraGabrielle M. Hernandez Barrera
- Alexis W. ThomasAlexis W. Thomas
- Mario IslasMario Islas
- Joanna L. KramerJoanna L. Kramer
- Lora NordstromLora Nordstrom
- Mary MulrowMary Mulrow
Open Access
Abstract
Influenza viruses are constantly evolving and are therefore monitored worldwide in the hope to reduce the burden of disease by annual updates to vaccine recommendations. We conducted genomic sequencing of 110 influenza A and 30 influenza B viruses from specimens collected between October 2023 and February 2024 in Arizona, USA. We identified mutations in the hemagglutinin (HA) antigenic sites as well as the neuraminidase (NA) gene in our samples. We also found no unique HA and NA mutations in vaccinated yet influenza-infected individuals. Real-time genomic sequencing surveillance is important to ensure influenza vaccine effectiveness.Keywords
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Funding Information
- Centers for Disease Control and Prevention (CDC U01 IP001180)
- Arizona State University (CDC U01 IP001180)
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