Benzpyrene Hydroxylase Induction by Polycyclic Hydrocarbons in Hamster Embryonic Cells Grown in vitro
Authors:
- 7 July 1967
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 157 (3784) , 75-76
Abstract
Treatment of hamster embryonic cells with 1,2-benzanthracene for 4 to 48 hours induced a three- to tenfold increase in the activity of benzpyrene hydroxylase. That the increase in enzyme activity was completely prevented by puromycin suggested an induction of enzyme synthesis.Keywords
This publication has 7 references indexed in Scilit:
- Differential Inhibition of Deoxyribonucleic Acid and Ribonucleic Acid Synthesis induced in Cultured Mammalian Cells by 7 : 12-DimethylbenzanthraceneNature, 1965
- The induction of benzpyrene hydroxylase in the isolated perfused rat liverBiochemical Pharmacology, 1965
- METHYLCHOLANTHRENE-INDUCED CHANGES IN RAT LIVER NUCLEAR RNAProceedings of the National Academy of Sciences, 1964
- HISTOCHEMICAL DEMONSTRATION OF REDUCED PYRIDINE NUCLEOTIDE DEPENDENT POLYCYCLIC HYDROCARBON METABOLIZING SYSTEMSJournal of Histochemistry & Cytochemistry, 1962
- Factors Influencing Drug Metabolism1962
- Amino Acid Metabolism in Mammalian Cell CulturesScience, 1959
- Substrate-Induced Synthesis And Other Properties Of Benzpyrene Hydroxylase In Rat LiverJournal of Biological Chemistry, 1957