Controversy
Authors:
- Victoria M. PakVPVictoria M. Pak
- Regina E. NailonRNRegina E. Nailon
- Linda A. McCauleyLMLinda A. McCauley
- 1 July 2007
- journal article
- review article
- Published by Wolters Kluwer Health in MCN: The American Journal of Maternal/Child Nursing
- Vol. 32 (4) , 244-249
Abstract
This article presents a review of extant literature that informs our current understanding of the effects of di-(2-ethylhexyl) phthalate (DEHP) exposure on neonates. Phthalates such as DEHP add flexibility to plastics. DEHP is a major component in the manufacturing of polyvinyl chloride devices commonly used in the healthcare setting. Premature and critically ill neonates and infants in the NICU are exposed to DEHP and may be at an increased risk for adverse health outcomes as a result. DEHP has been shown to be a developmental and endocrine disrupting toxicant and is a major component in polyvinyl chloride plastics, which are commonly found in medical equipment used in the NICU. Potential toxicities to infants in the NICU are a concern because infants' small body size and compromised physical condition necessitate a multitude of medical interventions, each increasing exposure levels. Expanding nurses' knowledge regarding DEHP research is important for implementing a precautionary approach to reduce DEHP exposure among NICU patients.Keywords
This publication has 12 references indexed in Scilit:
- How to Reduce DEHP in Your NICU: A Plan of Simple Steps to Promote ChangeNeonatal Network, 2006
- Estimated Daily Phthalate Exposures in a Population of Mothers of Male Infants Exhibiting Reduced Anogenital DistanceEnvironmental Health Perspectives, 2006
- PVC-plasticizer DEHP in medical products: do thin coatings really reduce DEHP leaching into blood?Perfusion, 2005
- Follow-Up Study of Adolescents Exposed to Di(2-Ethylhexyl) Phthalate (DEHP) as Neonates on Extracorporeal Membrane Oxygenation (ECMO) SupportEnvironmental Health Perspectives, 2004
- Exposure to Di-(2-Ethylhexyl) Phthalate Among Premature Neonates in a Neonatal Intensive Care UnitPediatrics, 2004
- Pediatric Exposure and Potential Toxicity of Phthalate PlasticizersPediatrics, 2003
- Mechanisms of phthalate ester toxicity in the female reproductive system.Environmental Health Perspectives, 2003
- Extraction of Diethylhexylphthalate from Total Nutrient Solution‐Containing Polyvinyl Chloride BagsJournal of Parenteral and Enteral Nutrition, 1989
- Identification and Measurement of Plasticizer in Neonatal Tissues after Umbilical Catheters and Blood ProductsNew England Journal of Medicine, 1975
- Migration of a Phthalate Ester Plasticizer from Polyvinyl Chloride Blood Bags into Stored Human Blood and Its Localization in Human TissuesNew England Journal of Medicine, 1972