Inactivation of myostatin by photooxygenation using functionalized d-peptides
- 3 January 2023
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in RSC Medicinal Chemistry
- Vol. 14 (2) , 386-392
Abstract
Myostatin-binding d-peptides functionalized with photocatalyst efficiently inactivate myostatin by photooxygenation and show no phototoxicity and high resistance to proteolytic enzymes, leading to the treatment of muscular atrophic diseases.Keywords
Funding Information
- Japan Society for the Promotion of Science (19K07001, 19H03356, 22J10632)
- Takeda Science Foundation
- Uehara Memorial Foundation
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