Supplementary Figures from MiR-30e-3p Influences Tumor Phenotype through MDM2/TP53 Axis and Predicts Sorafenib Resistance in Hepatocellular Carcinoma

Authors:
  • LGLaura Gramantieri
    Laura Gramantieri
  • DPDaniela Pollutri
    Daniela Pollutri
  • MGMartina Gagliardi
    Martina Gagliardi
  • CGCatia Giovannini
    Catia Giovannini
  • SQSantina Quarta
    Santina Quarta
  • MFManuela Ferracin
    Manuela Ferracin
  • ACAndrea Casadei-Gardini
    Andrea Casadei-Gardini
  • ECElisa Callegari
    Elisa Callegari
  • SCSabrina De Carolis
    Sabrina De Carolis
  • SMSara Marinelli
    Sara Marinelli
  • FBFrancesca Benevento
    Francesca Benevento
  • FVFrancesco Vasuri
    Francesco Vasuri
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Abstract
This file contains Supplementary Figures. SF1: Correlations between miR-30 family member in human tissues. SF2: Microarray analysis of miRNAs in the rat model. SF3: miR-30e locus and p53 regulation. SF4: MDM2 regulation by miR-30e-3p in HCC cells. SF5: MiR-30e-3p regulates cell growth and cell invasion in HCC cells. SF6: MiR-30e-3p regulates stem cell phenotype in HCC cells. SF7: MiR-30e-3p regulates drug resistance in TP53 deleted HepG2 cells. SF8: MiR-30e-3p regulates drug resistance in TP53 mutated Huh-7 cells. SF9: Circulating miR-30e-3p levels predicts sorafenib response in HCC preclinical models.