Neurophysiology of the Striated Urethral Sphincter in Multiple Sclerosis

Authors:
  • KNK. Nagendran
    K. Nagendran
  • BLB. Lecky
    B. Lecky
  • RKR. S. Kirby
    R. S. Kirby
  • CFClare J. Fowler
    Clare J. Fowler

Abstract
Summary Urethrovesical dysfunction is common in patients with multiple sclerosis. We present the results of urodynamic and neurophysiological studies in a series of 24 patients with multiple sclerosis associated with urinary symptoms. Urethral sphincter electromyography showed only minor abnormalities but studies of central conduction demonstrated abnormal sensory conduction in 88% and abnormal motor conduction in 80% of the patients studied. These abnormalities of central conduction correlated well with the urodynamic findings.

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