NINJ1: Bridging lytic cell death and inflammation therapy
Open Access
- 15 November 2024
- journal article
- review article
- Published by Springer Nature in Cell Death & Disease
- Vol. 15 (11) , 1-8
Abstract
NINJ1, a critical transmembrane protein in inflammation, governs diverse biological processes. Recent breakthroughs revealed NINJ1’s structural basis for plasma membrane rupture, which is directly linked to lytic cell death. This discussion explores NINJ1’s functions, focusing on its pivotal role in lytic cell death regulation and the latest advancements in targeted therapeutic interventions.Keywords
Funding Information
- Qiantang Scholars Fund in Hangzhou City Universit
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