Relations between prenatal sleep health and maternal weight retention 2 to 7 years after a first birth: the NuMoM2b-HHS
Authors:
- Marquis S HawkinsMHMarquis S Hawkins
- Michele D LevineMLMichele D Levine
- Namhyun KimNKNamhyun Kim
- Christina M PersonetteCPChristina M Personette
- Mattina A DavenportMDMattina A Davenport
- Andrea B KozaiAKAndrea B Kozai
- David PhanDPDavid Phan
- William GrobmanWGWilliam Grobman
- Jeanna T RyanJRJeanna T Ryan
- Angela C RanziniARAngela C Ranzini
Preprint
Abstract
Background: Poor prenatal sleep health is associated with greater gestational weight gain, but the contributions to longer-term maternal weight retention remain unclear. Purpose: To examine associations between prenatal sleep health across multiple domains and maternal weight retention 2 to 7 years after a first birth. Methods: Participants were from the nuMoM2b-Heart Health Study. Self-reported sleep was assessed during early (6 to 13 6/7 weeks) and mid-pregnancy (22 to 28 6/7 weeks) across six domains: regularity, quality, sleepiness, timing, efficiency, and duration. A multidimensional sleep health (MSH) score reflected the number of domains meeting healthy thresholds. Outcomes included maternal weight retention, total and substantial (>11 lbs.), from pre-pregnancy to 2 to 7 years after a first birth. Associations were estimated using adjusted linear regression for total weight retention and Poisson regression with robust variance for substantial weight retention. Results: The sample included 3,661 individuals with data in early (n = 2,962) and mid-pregnancy (n = 3,210). In early pregnancy, healthy sleep duration was associated with lower total weight retention, whereas healthy sleep regularity was unexpectedly associated with greater retention. In contrast, during mid-pregnancy, a higher MSH score was associated with a lower risk of substantial weight retention (RR = 0.96, 95% CI: 0.93 to 0.99). Healthy sleep duration and quality were the two individual domains associated with lower weight retention (2 to 3 lbs.). Conclusions: In a prospective cohort of pregnant nulliparous individuals, healthy prenatal sleep, particularly during mid-pregnancy, was associated with less maternal weight retention 2 to 7 years after delivery. Future studies should estimate the causal effects of sleep health on long-term maternal weight retention.Keywords
Funding Information
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (U10 HD063036)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (U10 HD063072)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (U10 HD063047)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (U10 HD063037)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (U10 HD063041)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (U10 HD063020)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (U10 HD063046)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (U10 HD063048)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (U10 HD063053)
- Clinical and Translational Science Institutes (UL1TR001108)
- Clinical and Translational Science Institutes (UL1TR000153)
- National Heart, Lung, and Blood Institute (U10‐HL119991)
- National Heart, Lung, and Blood Institute (U10‐HL119989)
- National Heart, Lung, and Blood Institute (U10‐HL120034)
- National Heart, Lung, and Blood Institute (U10‐HL119990)
- National Heart, Lung, and Blood Institute (U10‐HL120006)
- National Heart, Lung, and Blood Institute (U10‐HL119992)
- National Heart, Lung, and Blood Institute (U10‐HL120019)
- National Heart, Lung, and Blood Institute (U10-HL119993)
- National Heart, Lung, and Blood Institute (U10‐HL120018)
- National Heart, Lung, and Blood Institute (U01HL145358)
- National Center for Advancing Translational Sciences (UL‐1‐TR000124)
- National Center for Advancing Translational Sciences (UL‐1‐TR000153)
- National Center for Advancing Translational Sciences (UL‐1‐TR000439)
- National Center for Advancing Translational Sciences (UL‐1‐TR001108)
- National Center for Advancing Translational Sciences (U54 AG065141)
- National Center for Advancing Translational Sciences (U54 AG094168)
- Barbra Streisand Womens Cardiovascular Research and Education Program
- Erika J. Glazer Womens Heart Research Initiative
- Cedars-Sinai Medical Center, Los Angeles