Allosteric modulation of metabotropic glutamate receptors: Structural insights and therapeutic potential
- 14 July 2010
- journal article
- review article
- Published by Elsevier in Neuropharmacology
- Vol. 60 (1) , 66-81
Abstract
No abstract availableKeywords
This publication has 212 references indexed in Scilit:
- Activation of type 5 metabotropic glutamate receptors attenuates deficits in cognitive flexibility induced by NMDA receptor blockadeEuropean Journal of Pharmacology, 2010
- Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampusNeuropharmacology, 2009
- Discovery and Characterization of Novel Subtype-Selective Allosteric Agonists for the Investigation of M1 Receptor Function in the Central Nervous SystemACS Chemical Neuroscience, 2009
- Positive Allosteric Modulation of mGluR5 Receptors Facilitates Extinction of a Cocaine Contextual MemoryBiological Psychiatry, 2009
- Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophreniaTrends in Pharmacological Sciences, 2009
- Correction of Fragile X Syndrome in MiceNeuron, 2007
- Positive Allosteric Modulation of Metabotropic Glutamate 5 (mGlu5) Receptors Reverses N-Methyl-D-Aspartate Antagonist-Induced Alteration of Neuronal Firing in Prefrontal CortexBiological Psychiatry, 2007
- Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trialNature Medicine, 2007
- Cyclothiazide selectively inhibits mGluR1 receptors interacting with a common allosteric site for non-competitive antagonistsNeuropharmacology, 2006
- Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEPNeuropharmacology, 2005