A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens

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Abstract
A peptide hydrogel with an antimicrobial activity is developed as a bandage contact lens. The antimicrobial activity is enhanced with the addition of the biomolecules penicillin G or poly-ε-lysine and is positive against Staphylococcus aureus and Escherichia coli. The lens is also noncytotoxic toward a human corneal epithelial cell line and as a consequence is of great potential as a drug-eluting bandage lens replacing conventional corneal ulcer treatment.
Funding Information
  • Engineering and Physical Sciences Research Council (EP/M002209/1)

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