Growth and development in preterm infants receiving fluoroquinolones

Authors:
  • SBStella de Ben
    Stella de Ben
  • MWMarina Weinberger
    Marina Weinberger
  • GBGraciela Beltrami
    Graciela Beltrami
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Abstract
Growth and development were followed in 7 preterm newborn infants who received fluoroquinolones in the neonatal period. Quinolones were used as a "life saving" therapy in cases of sepsis caused by bacterial agents sensitive only to these drugs. Two other groups of neonates matched for gender, birth weight and gestational age served as controls. Although the quinolone group had more severe illness, no statistically significant differences were observed in growth and development between the groups. No osteoarticular problems or joint deformities were observed in the quinolone group. Therefore, quinolones could be a therapeutic option for newborns with sepsis caused by multiply resistant organisms.